Up in smoke: Understanding knowledge gaps for cannabis edibles

  • Criminalisation of cannabis stagnated research outside the realm of addiction and biomedical studies across Canada before the Cannabis Act (C-45) and eventual legalisation on October 17, 2018.
  • Nevertheless, massive voids exist in scientific knowledge of the chronic effects of oral administration of isolated metabolically active cannabinoids (> 100 unique molecules) and, to a lesser extent, but still potentially an issue the terpenoids, flavonoids, and alkaloids.
  • From henceforth, the author does not consider, nor address issues on overall ethical considerations of general legalisation, addiction, or health aspects that are not unique to edibles.
  • Unlike alcohol and even remarkably different than vaped or pyrolysed cannabis, consumption of edibles containing metabolically active molecules introduces unique challenges especially significant to legislation, regulation, and ultimately enforcement.

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